EFFECTS OF GREEN SILVER NANO PARTICLES ON THE RESISTENCE GRAM NEGAVTIVE BACTERIA
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Author:
SABIRA PARVEEN
Citable URI :
https://vspace.vu.edu.pk/detail.aspx?id=141
Publisher :
Virtual University
Date Issued:
9/1/2018 12:00:00 AM
Abstract
Escherichia coli and Salmonella typhimurium are the type of gram negative
bacteria that can cause different healthcare associated infections. Silver nanoparticles
are considered to be used in various applications against bacteria that are opposed to
to common antibiotics or even multidrug resistant bacteria as the E. coli and S.
typhimurium.
In this study, the facile methodology is used for the synthesis of tetracycline
capped AgNPs as reducing and capping agent. The formation of the AgNPs was
examined by UV–Vis spectroscopy. This characterization confirmed the formation of
AgNPs by exciting the surface Plasmon resonance at 407 nm. The Fourier Transform
Infrared Spectroscopy (FT-IR) and X-Ray Diffraction (XRD) further inveterate the
face centered cubic structure in pure phase. This work was also evaluated the
antibacterial activity of synthesized silver nanoparticles against examined bacterial
strains as E. coli and S. typhimurium resistant to large number of antibiotics.
Regarding antibacterial susceptibility tests, studied bacterial strains showed great
sensitivity for synthesized silver nanoparticles. These activities were dose dependent
when compared to tetracycline. By using well diffusion method a considerable Zone
of Inhibition (ZOI) towards bacterial strains were observed.
This high antibacterial potential can be utilized against others lethal
pathological bacterial strain for future pharmaceutical products. Moreover, these
findings could also pave the way for further investigations such as against sewerage
water and waste material reduction.
URI :
https://vspace.vu.edu.pk/details.aspx?id=141
Citation:
Perveen, S (2017), EFFECTS OF GREEN SILVER NANO PARTICLES ON THE RESISTENCE GRAM NEGAVTIVE BACTERIA. Virtual University of Pakistan.(Lahore, Pakistan).
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Final Version
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